Osteitis Fibrosa – Causes, Symptoms, Diagnosis, And Treatment
What is osteitisfibrosa?
Osteitisfibrosa, also called osteitisfibrosacystica, is a rare complication of hyperparathyroidism. This condition results in certain bones becoming abnormally weak and deformed.
What causes osteitisfibrosa?
High levels of parathyroid hormone in the blood (hyperparathyroidism) cause osteitisfibrosa.
There are 4 parathyroid glands in the neck. These tiny glands produce parathyroid hormone (PTH). PTH is responsible for controlling calcium, phosphorus, and vitamin D levels in the blood, which is important for bone health.
Excessive parathyroid hormone (hyperparathyroidism) can lead to increased bone breakdown, which can cause bones to become weaker and more fragile. Many people with hyperparathyroidism develop osteoporosis. Not all bones respond to PTH in the same way. Some develop abnormal areas where the bone is very soft and has almost no calcium in it. This is called osteitisfibrosa.
In rare cases, parathyroid cancer causes osteitisfibrosa.
What are the possible complications of osteitisfibrosa?
The following are the complications of osteitisfibrosa:
- Bone fractures
- Deformities of bone
What are the symptoms of osteitisfibrosa?
The main symptom of osteitisfibrosa is bone pain or tenderness. Fractures (breaks) in the arms, legs, or spine or other bone problems are the other symptoms.
Hyperparathyroidism itself can cause any of the following:
- Frequent urination
How is osteitisfibrosa diagnosed?
Your doctor will perform a physical exam, review your symptoms, and do some tests. The doctor may suspect osteitisfibrosa if the blood test shows a high level of calcium, parathyroid hormone, and alkaline phosphatase (a bone chemical). Phosphorus level in the blood may be low.
The doctor confirms the diagnosis if x-rays show thin bones, fractures, bowing, and cysts. Teeth x-rays may also be abnormal.
People with hyperparathyroidism are more likely to have osteopenia (thin bones) or osteoporosis (very thin bones) than to have full-blown osteitisfibrosa.
How is osteitisfibrosa treated?
Doctors may treat most people with osteitisfibrosa by removing abnormal parathyroid glands surgically. If surgery is not possible, medicines are given to lower calcium level and followed with blood tests and bone measurements.
This feature is for informational purposes only and is not intended to substitute the expert guidance of a doctor. We advise seeing a doctor if you have any health concerns.